estrogen-related receptor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7904	SR 19881		Estrogen/progestogen Receptor
	SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay).		Estrogen/progestogen Receptor
T0593	XCT790		Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Autophagy
	XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).
T5835	PROTAC ERRα ligand 2		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist( IC50 : 5.67 nM)		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T15191	PROTAC ERRα ligand 1		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	PROTAC ERRα ligand 1 is an α (ERRα) antagonist of estrogen-related receptor (IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively).		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T8370	GSK5182		Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Reactive Oxygen Species
	GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
T7709	(E/Z)-GSK5182	GSK5182(Z/E)	Estrogen/progestogen Receptor , ROS
	(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating ...		Estrogen/progestogen Receptor , ROS
T0760	Cholesterol	Cholesterin,Cholesteryl alcohol	Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
	Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is widely found in the cell membranes of animals and is also us...		Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
T77577	SLU-PP-332		Estrogen/progestogen Receptor
	SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ with EC50 values of 98, 230, and 430 nM, respectively.SLUPP-332 enhances mitochondrial function and cellula...		Estrogen/progestogen Receptor
T11230	ERRα antagonist-1	ERR+/- antagonist-1,ERRa antagonist-1	Estrogen/progestogen Receptor
	ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coac...		Estrogen/progestogen Receptor
T18609	PROTAC ERRα Degrader-2		Others
	PROTAC ERRα Degrader-2 is a compound consisting of an MDM2 ligand binding group, a linker, and an estrogen-related receptor alpha (ERRα) binding group. This compound is designed to specifically degrade estrogen-related r...		Others
T13700	GDC-0927 Racemate	SRN-927 Racemate	Others
	GDC-0927 Racemate is a degrader of estrogen receptor, is used in the research of ER-related diseases, potently inhibits ER-α activity, with an IC50 of 0.2 nM.		Others
T18651	(rel)-PROTAC ERRα Degrader-1		Others
	(rel)-PROTAC ERRα Degrader-1 is a relative configuration of PROTAC ERRα Degrader-1, which is an estrogen-related receptor alpha (ERRa) degrader. PROTAC ERRα Degrader-1 consists of an MDM2 ligand binding moiety, a linker ...		Others
T40349	DS45500853
	DS45500853, an estrogen-related receptor α (ERRα) agonist, acts as an inhibitor of the binding interaction between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain ...
T60441	DK3
	DK3 is a potent and selective agonist of estrogen-related receptor alpha (ERRα). ERRα is a potential drug target for cancer and metabolic diseases [1].
T60674	DK1
	DK1 is a potent estrogen related receptor modulator. DK1 impacts the activity of ERRα receptor and reduces blood glucose. DK1 shows the potential in the diabetes research [1].
T39838	(S,R,S)-AHPC-C7-amine	VH032-C7-amine,(S,R,S)-AHPC-C7-amine
	(S,R,S)-AHPC-C7-amine, also known as VH032-C7-amine, is a chemically synthesized conjugate that functions as an E3 ligase ligand-linker. This compound combines the VH032-based VHL ligand with a specific linker designed f...
T11231	ERRγ Inverse Agonist 1		Estrogen/progestogen Receptor
	ERRγ Inverse Agonist 1 (Compound 12) is a potent, selective and orally bioavailable Estrogen-related Receptor grammar (ERRγ) inverse agonist (IC 50=40 nM) [1].		Estrogen/progestogen Receptor
T39651	(S,R,S)-AHPC-C5-NH2	(S,R,S)-AHPC-C5-NH2,VH032-C5-NH2
	(S,R,S)-AHPC-C5-NH2, also known as VH032-C5-NH2, is a synthetic compound designed as an E3 ligase ligand-linker conjugate. This compound combines the VH032-based von Hippel-Lindau (VHL) ligand with a linker, enabling it ...
TMA0424	Martynoside		ROS
	Martynoside is a natural selective estrogen receptor modulator, which has antioxidative, anti-muscle fatigue, anticancer and antimetastatic activities. Martynoside has the potential of antagonizing sports anaemia, the me...		ROS
T61923	ERRα antagonist-2
	ERRα antagonist-2 (Compound 11) is a potential Reverse agonist of ERR α (estrogen receptor related receptor α) (IC50=0.80 μ M). ERRα antagonist-2 can inhibit the migration and invasion of ER-negative MDA-MB-231 cells. ER...